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Reimbursement criteria
Eligibility recommendations
Treatment centres

Indication

YESCARTA® is indicated for the treatment of adult patients with diffuse large B-cell lymphoma (DLBCL) and high-grade B-cell lymphoma (HGBL) that relapses within 12 months from completion of, or is refractory to, first-line chemoimmunotherapy.

YESCARTA® is indicated for the treatment of adult patients with relapsed or refractory (r/r) DLBCL and primary mediastinal large B-cell lymphoma (PMBCL), after two or more lines of systemic therapy.

Yescarta Belgian reimbursement criteria
Yescarta as new 2L DLBCL standard of care: a paradigm shift
  1. Brijs et al. Updated BHS Guidelines DLBCL 2024, BJH Vol 15 June 2024
  2. Hayden PJ, Roddie C, Bader P, et al. Management of adults and children receiving CAR T-cell therapy: 2021 best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE) and the European Haematology Association (EHA). Ann Oncol. 2022;33(3):259-75.

CAR T eligibility is broader than transplant eligibility

CAR T eligibility is broader than transplant eligibility
Map of the Benelux

UZ Leuven - Gasthuisberg

Herestraat, 49
3000 Leuven

Contact:

016 34 17 73016 34 68 80

Prof Dr Peter Vandenberghe

CAR-T Coördinator:

Benedicte Dubois

CART@uzleuven.be

Contact:

09 332 58 13

Prof Dr Fritz Offner

Prof Dr Tessa Kerre

Dr Ciel De Vriendt

Dr Willem Daneels

CAR-T Coördinators:

Charlotte Mestdagh

Amy Senave

Astrid Van Bastelaere

cart.hematologie@uzgent.be

Contact:

04 366 81 7304 366 82 56

Prof Dr Jo Caers: jo.caers@chu.ulg.ac.be

Dr Christophe Bonnet: christophe.bonnet@chuliege.be

Dr Claire Maquet: cmaquet@chuliege.be

Dr Céline Grégoire: celine.gregoire@chuliege.be

CAR-T Coördinator:

Christelle Andrianne:

christelle.andrianne@chuliege.be

Cliniques universitaires Saint-Luc

Av. Hippocrate, 10
1200 Bruxelles

CAR-T Coördinator:

Burçin Bilge

burcin.bilge@saintluc.uclouvain.be

Contact:

03 821 24 19

Prof Dr Sébastien Anguille

CAR-T Coördinators:

Sophie Van Herenthals
Pascale De Graef

CART.hematologie@uza.be

AZ Sint-Jan Brugge

Ruddershove 10
8000 Brugge

Contact:

050 45 99 78050 45 99 79

Dr Sylvia Snauwaert

Dr Alexander Schauwvlieghe

CAR-T Coördinators:

Veronique Stockx

Veerle Peters

Kéhindé Louagie

HoST.verpleegkundigen@azsintjan.be

Contact:

02 541 72 5902 541 38 88

Dr Marie Maerevoet: marie.maerevoet@hubruxelles.be

Dr Fulvio Massaro: fulvio.massaro@bordet.be

Prof Nathalie Meuleman: nathalie.meuleman@hubruxelles.be

Prof Virginie Dewilde: virginie.dewilde@hubruxelles.be

CAR-T Coördinator:

Jessica Pinto Oliveira:

cart.bordet@hubruxelles.be

Contact:

+35244112084

Dr Sigrid Dewilde

sec.hemato@chl.lu

CAR-T Coördinator:

Hubert Chloe

Hubert.chloe@chl.lu